YALEPIC® miRNA Isolation Kit (No DNase I) is suitable for the extraction of small RNAs (miRNA, <200 nt) from fewer than 5 × 106 eukaryotic cells or less than 100 mg of animal tissues. The obtained miRNAs are of high purity without large RNAs or genomic DNA contamination, can be directly used for Microarrarys, Northern blot, RT-PCR and miRNA library preparation, etc.