YALEPIC^® MagSEL DNA Size Selection Kit(for NGS)

The kit stably recovers DNA fragments as small as 100 bp. By adjusting the bead-to-sample ratio, it can size-select up to 10 kb large genomic DNA fragments, accommodating both small NGS library fragments and large gDNA purification.

The 5 ml size (YNQ46001-01) is suitable for small-scale, manual NGS library preparation in research labs. The 60 ml size (YNQ46001-03) is designed for high-throughput laboratories and automated workstations for batch sample processing.

Yes. The selection principle, operating ratios, and fragment size selection range are consistent with AMPure XP. The purification recovery rate is comparable to imported products while significantly reducing NGS library preparation reagent costs.

Freezing is strictly prohibited. Freezing damages the surface functional groups of the beads, resulting in loss of DNA binding capacity. Once frozen, the kit must be discarded. Store at 2-8 degrees C.

Four common causes: (1) Beads not equilibrated to room temperature before use; (2) Insufficient mixing of beads and sample; (3) Incorrect bead addition ratio; (4) Over-drying of beads. Optimizing these steps per the protocol will improve recovery.

Fully compatible. The buffer formulation is optimized for automated platforms. Mainstream high-throughput workstations can use it directly without additional formulation adjustments.

Appropriately reduce the bead-to-sample ratio and use a double-sided size selection approach to efficiently remove primer and adapter-dimer impurities smaller than 100 bp, improving NGS library purity.

Only 80% ethanol (freshly prepared) is needed. The formulation does not contain phenol, chloroform, or other organic solvents, ensuring safe and non-toxic operation.

The beads can be used for general PCR product purification, restriction enzyme digest recovery, plasmid purification, and other molecular biology experiments. It is a universal DNA purification bead kit.

It can only be kept at room temperature (25 degrees C) for 1-3 days. For long-term storage, it must be kept at 2-8 degrees C. Prolonged room temperature storage accelerates bead sedimentation and degradation.

Calibrate pipettes to ensure accurate dispensing, strictly follow the protocol’s bead ratios, and thoroughly vortex the bead suspension before dispensing.

The beads in this kit are single-use consumables. Once DNA is adsorbed, it cannot be desorbed or regenerated. Reuse is not recommended as it would affect subsequent selection performance.