YALEPIC® Urine cfDNA Storage Tube——Ambient-Temperature Cell-Free DNA Preservation for Non-Invasive Liquid Biopsy

Time：2026-07-29

Non-Invasive Liquid Biopsy Sample Collection

YALEPIC^® Urine cfDNA
Storage Tube

Ambient-Temperature Cell-Free DNA Preservation for Non-Invasive Liquid Biopsy

The YALEPIC® urine cfDNA storage tube stabilizes cell-free DNA in urine for 7 days at 4–37°C — no cold chain, no centrifugation rush. NMPA & CE certified liquid biopsy sample collection, purpose-built for non-invasive cfDNA preservation in clinical diagnostics, NGS sequencing, and population-scale screening.

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📊 Performance at a Glance

4–37°C
Ambient storage & transport — no cold chain

7days
Reliable cfDNA preservation at standard conditions

NMPA+CE
Dual regulatory certification for clinical use

3sizes
10 / 50 / 100 mL — plus custom volumes

✔ NMPA certified medical device
✔ CE marked for in-vitro diagnostics
✔ Sterile & clinically validated
✔ Compatible with leading extraction kits

Product Introduction

What Is the YALEPIC^® Urine cfDNA Storage Tube?

The YALEPIC® urine cfDNA storage tube is a specialized liquid biopsy sample collection device engineered for ambient-temperature cell-free DNA preservation in urine specimens. Unlike conventional urine collection methods that require immediate freezing or centrifugation, this tube stabilizes cfDNA for up to 7 days at 4–37°C, enabling non-invasive liquid biopsy workflows without cold-chain dependence.

Dual-certified with NMPA and CE marks, it supports urine DNA collection for urological oncology detection, non-invasive prenatal testing (NIPT), urinary pathogen identification, and large-scale population screening. The proprietary EDTA-based protectant formula suppresses nuclease activity and prevents urothelial cell lysis, ensuring high-quality cfDNA preservation compatible with mainstream magnetic-bead and column-based extraction kits for NGS, qPCR, and methylation analysis.

By eliminating the cold chain, the YALEPIC® tube makes ambient temperature DNA stabilization a practical reality for inter-regional shipping, home self-collection, and batched laboratory processing — reducing logistics cost while maintaining nucleic-acid integrity for clinical-grade results.

Product Advantages

Why Choose YALEPIC^® for Urine cfDNA Preservation?

Urine is rich in urea, salts, and nucleases — cfDNA degrades within hours by default. YALEPIC® changes the rule, making at-home and cross-region urine collection a reality for liquid biopsy.

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Ambient-Temperature Stability

Stable from 4–37°C across all seasons and logistics routes. Inter-regional shipping without refrigerated cold chain cuts medical-logistics cost dramatically and enables ambient temperature DNA stabilization.

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7-Day cfDNA Preservation

Cell-free DNA remains intact for 7 days at standard conditions, ensuring nucleic-acid integrity for NGS, qPCR, and downstream analytics. Reliable cfDNA preservation without time pressure.

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Dual-Protection Technology

EDTA anticoagulant + composite protectant suppresses nuclease activity and prevents cell lysis — reducing genomic-DNA contamination that could interfere with cfDNA detection.

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Non-Invasive & Patient-Friendly

No venipuncture required. Ideal for non-invasive liquid biopsy, mass population screening, prenatal NIPT, and chronic-disease follow-up — comfortable for patients, simple for collectors.

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NMPA & CE Dual Certified

Clinical-grade sterile tube interior meets IVD sample-collection standards. NMPA & CE certified medical device, regulatory-ready for clinical and research use.

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Flexible & Customizable

Three stock sizes (10 / 50 / 100 mL) plus custom tube volumes and packaging. Same-day shipping for stock items; dedicated quotation for bulk procurement.

How It Works

Two Layers of Defense,
One Stable Sample

From the moment urine enters the tube, the specialized urine-nucleic-acid protectant begins working — immediately inhibiting the high nuclease activity unique to urine samples for reliable cell-free DNA preservation.

Nuclease Suppression

EDTA anticoagulant chelates divalent cations, blocking nuclease-driven degradation and preserving fragile cell-free DNA fragments.

Cell-Lysis Blockade

Composite protectant fixes shed urothelial cells, preventing genomic-DNA release that would contaminate the cfDNA fraction.

Ambient Stabilization

cfDNA remains intact at 4–37°C for up to 7 days — enabling home self-collection and long-haul transport without cold chain.

Applications

Built for Clinical & Research Workflows

Preserved samples are compatible with mainstream magnetic-bead and column-based commercial cfDNA extraction kits, ready for every major sequencing platform.

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Urological Oncology

Liquid biopsy for bladder, kidney & prostate cancer cfDNA mutation detection.

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Methylation Screening

Urine cfDNA methylation biomarker screening for early disease signals.

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Pathogen Detection

Microbial cfDNA testing for urinary-tract infections.

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Prenatal & Screening

Non-invasive prenatal testing and large population health screening.

Product Specifications

Three Ready Sizes, Custom on Request

Stock ships same-day. Bulk procurement and custom volumes available with dedicated quotation.

Catalog No.	Specification	Pack Size	Suggested Use
YS21041-50	10 mL / tube	50 tubes / box	Individual & small-batch sampling
YS21042	50 mL / tube	30 tubes / box	Clinical labs & routine batches
YS21043	100 mL / tube	20 tubes / box	Cohort studies & high-volume collection

📦 Storage of empty tubes: 4–25°C, cool & dry · Shelf life 12 months · Transport: 4–37°C ambient.

FAQ

Frequently Asked Questions

Everything you need to know about the YALEPIC® urine cfDNA storage tube for cell-free DNA preservation and non-invasive liquid biopsy.

What is a urine cfDNA storage tube?

A urine cfDNA storage tube is a specialized medical device designed for liquid biopsy sample collection that preserves cell-free DNA (cfDNA) in urine specimens at ambient temperature. The YALEPIC® urine cfDNA storage tube uses an EDTA-based protectant formula to stabilize cfDNA for up to 7 days at 4–37°C, enabling non-invasive liquid biopsy without cold-chain logistics. It is NMPA and CE certified for clinical in-vitro diagnostic and research use.

How long does the YALEPIC® tube preserve cell-free DNA in urine?

The YALEPIC® urine cfDNA storage tube preserves cell-free DNA in urine for up to 7 days at standard ambient conditions (4–37°C). This extended stabilization window covers cross-region shipping, batched sequencing schedules, and home self-collection workflows without requiring refrigeration or immediate processing — making cfDNA preservation practical for real-world clinical settings.

What temperature range does the urine cfDNA storage tube support?

The YALEPIC® urine cfDNA storage tube supports ambient temperature DNA stabilization from 4°C to 37°C. This wide-range temperature tolerance eliminates cold-chain requirements for urine DNA collection and transport, making it suitable for year-round logistics across different climates and regions.

How does the cell-free DNA preservation technology work?

The YALEPIC® tube uses a dual-protection cell-free DNA preservation technology. First, EDTA anticoagulant chelates divalent cations to suppress nuclease-driven cfDNA degradation. Second, a composite protectant fixes shed urothelial cells to prevent cell lysis and genomic-DNA release that would contaminate the cfDNA fraction. Together, these mechanisms maintain cfDNA integrity for downstream NGS, qPCR, and methylation analysis.

Is the YALEPIC® urine cfDNA storage tube certified for clinical use?

Yes. The YALEPIC® urine cfDNA storage tube is dual-certified with NMPA (China National Medical Products Administration) and CE (European Conformity) marks. The tube interior is sterile and meets clinical sample-collection standards for in-vitro diagnostic (IVD) and research applications — NMPA & CE certified for global clinical use.

Which extraction kits are compatible with preserved urine cfDNA samples?

Urine cfDNA samples preserved in the YALEPIC® tube are compatible with mainstream magnetic-bead and column-based commercial cfDNA extraction kits. For optimal NGS library preparation, the YALEPIC® magnetic-bead urine cfDNA extraction kit is recommended. Preserved samples work with all major downstream platforms including Illumina, Thermo Fisher, and MGI sequencers.

What applications is the urine cfDNA storage tube used for?

The YALEPIC® urine cfDNA storage tube is used for non-invasive liquid biopsy applications including: urological oncology (bladder, kidney, and prostate cancer cfDNA mutation detection), urine cfDNA methylation screening for early disease signals, urinary tract pathogen detection via microbial cfDNA testing, non-invasive prenatal testing (NIPT), and large-scale population health screening programs.

What sample volumes and packaging options are available?

The YALEPIC® urine cfDNA storage tube is available in three stock sizes: 10 mL (Catalog No. YS21041-50, 50 tubes/box), 50 mL (Catalog No. YS21042, 30 tubes/box), and 100 mL (Catalog No. YS21043, 20 tubes/box). Custom tube volumes and packaging configurations are available upon request for bulk procurement. Stock items ship same-day.

Ready to Stabilize Your Urine Samples?

Request a quote, order samples, or discuss custom specifications with our technical team. Domestic stock ships the same day.

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